So I'm not willing to make the commitment that option takes. Instead I've come up with this.
Y_______o.o.0.o.o_____SE
...........S............................._____X
......................Q
......................F
So the main advantages of this are that it's simpler. There is no switching between sides. The X is your super star running back. There is misdirection, and there is an audible to a power house sweep play.
OUTSIDE STUFF
The QB should be able to audible to either of these two plays at any time.
Jet 27 Sweep
The bread and butter run play is the sweep. The QB should always be able to audible to this if he sees that the opponent is not respecting the Slot Receiver's ability to crack the DE. The QB sends the X in motion, and does a backwards turn to give the ball to the X. The S and Y crack the DE and first contain, and the F kicks the 2nd contain. The Left guard can pull for good measure.
Flats 28 Bubble
The next play is the bubble sweep. It's the equivalent of the sweep in the other direction. The F will motion in the wrong direction, and the SE will block who ever is over the X. The Right tackle will leave his man and block the person over the SE. The Right guard can do the same after two one second. The X's path is more up the middle, but they're allowed to go outside if that's more open.
Flats 28 Bubble
The sister play of the bubble is the flats pass. Again the F goes in motion to the left. This time the F runs a flats, the S runs a five yard out, and the Y runs a go. This is both a designed play, but the QB has the option to send the F in motion at any time. This should que the bubble screen as well. However, since this is an audible, your tackle wont know to release, and since this is a designed play on the other side, the QB can always choose to throw the flats, just in case he sees no one on that side, but I would be careful about letting him choose.
BELLY
I want the belly to be the ying to the passing game's yang. The FB is going to be a quick hitter with the ability to beat up linebackers who have gotten too used to backing up. He should almost always get 2 yards, if not five. Ideally it's the same play to each side. It's either a 34, 32, 31, or 33 dive with GOOD blocking. Your best result is probably going to be the 1s and 2s. The receivers are going to run arrow routes, the slot will block the MLB.
If you want, you can motion the X around, but that's not going to tell them it's a run. This is a way to condition them, then switch.
MISDIRECTION
Jet Fake, 34 counter:
The X goes in motion, the QB does his reverse pivot to meet him, and the F takes two counter steps to get in position. After the fake hand off, the F launches on the ball going towards the 4 hole. The LG and S both pull underneath. The Center and right side of the line all use GDL blocking. The LT seals the DT, the misdirection should distract the DE and hopefully some of the linebackers. It's a good way to condition, then switch.
Jet Fake, 16 Half Spin:
The X goes in motion, and the QB preforms his half pivot to meet him. This time he keeps it and runs to the 6 hole. He is aided by the LG and S, the blocking is similar to the last play. The F is committed to the fake and runs in front of the X.
Jet Fake, 15 Full Spin:
The X goes in motion, the the QB preforms his half pivot. This time he keeps it and completes the spin to run at the 5 hole. This time he is aided by the F who takes a more down hill angle to kick out the first contain, the RG who helps kick out the DE, and the Slot, who takes the MLB.
The spin and half spin should be run with just a one second delay on the snap to allow for the motion man to be inside the line. If the QB has to wait even one second to present the fake, he's not going to make it. He'll get hit by the back side DE.
On top of that, there's the standard DC run and shoot passing game. The blocking works by replacing the TE with the slot. If they decide to line up a DE inside the slot, they should be vulnerable to the sweep. This forces the DE outside, which achieves the same objective as before, and it allows your tackle to do a bucket step. Your F should kick out the twin's side DE. As always, you should be very good at slants and QB draw plays. Finally, the formation can adjust to the field position. If you're twins are backed up to one sideline, the twins right can bunch to 5 and 3 yards from the tackle, if they're on the open side, they can open to 7 and 5 yards. They can even go further if you feel your QB has the arm.
So that's 7 plays total. It's complex, and there there are five different blocking schemes. So the complexity is shared with the offensive line, rather than just the running backs.